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Dr. Julie  Pollock
Dr. Julie Pollock
Assistant Professor of Chemistry

My lab utilizes chemical biology techniques, biochemical methods, and organic synthesis to understand breast cancer and lung cancer development and progression. In particular, we are interested in nuclear receptor function, phosphorylation signaling pathways, and the link between cancer and inflammation.

Grants and Fellowships

2017: Jeffress Trust Award in Interdisciplinary Research

2016: Mary Louise Andrews Award for Cancer Research, Virginia Academy of Sciences

2013-2014: NIH Postdoctoral Fellowship in Endocrine, Developmental, and Reproductive Toxicology

2011: ACS Biological Division Travel Grant


Strategies towards ligand-selective modulation of nuclear receptors. Institute for Structural Biology, Drug Discovery and Development. Virginia Commonwealth University, Richmond, VA, May 2016.

Pollock, J. A.; Saijo, K.; Glass, C. K.; Katzenellenbogen, J. A. Characterization of Estrogen Receptor Ligands in Microglia-Mediated Inflammation. Interdisciplinary Environmental Toxicology Seminar Series, University of Illinois, Urbana, IL, February 2014.

Pollock, J. A.; McCafferty, D.G. LSD1: Inhibition and Implications in Breast Cancer. Duke University Breast Cancer Forum, Durham, NC, September 2011.

Selected Publications

Christenson, J.L.; Butterfield, K.T.; Spoelstra, N.S.; Norris, J.D.; Josan, J.S.; Pollock, J.A.; McDonnell, D.P.; Katzenellenbogen, B.S.; Katzenellenbogen, J.A.; Richer, J.K. “MMTV-PyMT and derived Met-1 mouse mammary tumor cells as models for studying the role of the androgen receptor in triple-negative breast cancer progression.” Horm. Canc. 2017, 8(2), 69-77.

Pollock, J.A.; Wardell, S.E.; Parent, A.A.; Stagg, D.B.; Ellison, S.J.; Alley, H.M.; Chao, C.A.; Lawrence, S.A.; Stice, J.P.; Spasojevic, I.; Baker, J.G.; Kim, S.H.; McDonnell, D.P.; Katzenellenbogen, J.A.; Norris, J.D. “Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer.” Nature: Chem. Biol. 2016, 12, 795-801.

Pollock, J.A.; Kim, S.H.; Katzenellenbogen, J.A. “Imidoyl dichlorides as new reagents for the rapid formation of 2-aminobenzimidazoles and related azoles.” Tetrahedron Lett. 2015, 26, 6097-6099.

Nwachukwu, J. C.; Srinivasan, S.; Bruno, N. E.; Parent, A. A.; Hughes, T. S.; Pollock, J. A.; Gjyshi, O.; Cavett, V.; Nowak, J.; Garcia-Ordonez, R. D.; Houtman, R.; Griffin, P. R.; Kojetin, D. J.; Katzenellenbogen, J. A.; Conkright, M. D.; Nettles,  K. W. “Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.” eLife 2014, 3, e02057.

Pollock, J. A.; Larrea, M. D.; Jasper, J. S.; McDonnell, D. P.; McCafferty, D. G. “Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and independent manners.” ACS Chem. Biol. 2012, 7, 1221-1231.

Ph.D., Duke University
Contact Information
C308 Gottwald Center for the Sciences
(804) 484-1578
(804) 287-1897 (Fax)
Areas of Expertise
Chemical Biology
Organic Chemistry