Dr. Jonathan Dattelbaum
Assistant Professor of Chemistry
D-300
Office: 804-484-1587
Fax: 804-287-1897
E-mail
Teaching:
Biochemistry
Research:
Research in the Dattelbaum Lab focuses on the rational design of fluorescent protein biosensors. We are interested in the design of a novel biosensor for glutamate, an important neurotransmitter. The constructed optical biosensor will be used to measure glutamate concentrations in neuronal cell culture. The second main project in the lab involves the design of novel fluorescent peptides. The aim of this research is to provide new fluorescent tags for protein trafficking, as well as for the development of genetically-encodable biosensors
Education:
Ph.D. - University of Maryland
Selected Publications:
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Dattelbaum, J.D., Lockatell, V., Johnson, D., and Mobley, H.L.T. (2003) UreR, the transcriptional activator of the Proteus mirabilis urease gene cluster, is required for urease activity and virulence in experimental urinary tract infection, Infect. Immun., 171, 1026-1030. Poore, C.A., Coker, C., Dattelbaum, J.D. and Mobley, H.L.T. (2001) Identification of the Domains of UreR, an AraC-like transcriptional Regulator of the Urease Gene Cluster in Proteus mirabilis, J. Bacteriol., 183, 4526-4535. Dattelbaum, J.D. and Lakowicz, J.R. (2001) Optical Detection of Glutamine using a Genetically Engineered Protein. Anal. Biochem., 291, 89-95. Piszzek, G., Maliwal, B.P., Grycsynski, I., Dattelbaum, J.D. and Lakowicz, J.R. (2001). Multi-photon Ligand-Enhanced Excitation of Lanthanides, J. Fluorescence, 11, 101-107. Dattelbaum, J.D., Abugo, O., and Lakowicz, J.R. (2000) Characterization of a Sulfhydryl-Reactive Rhenium Metal-Ligand Complex. Bioconjugate Chem., 11, 533-36. Lackowicz, J.R., Dattelbaum, J.D., and Gryczynski, I. (1999) Quantitative Intensity Measurements in Scattering Media. Sensors and Actuators, 60, 1-7.  |
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